Foli Pill™ Tablets

L-Methylfolate 400mcg


Foli Pill™ contains folate in the form of L-Methylfolate which is the biologically active folate isomer. L-Methylfolate is the body’s preferred form of folate because it is directly usable by the human organism for certain metabolic processes. There are well documented studies which have established folic acid’s ineffectiveness regarding inherited disorders of folate transport and metabolism. These disorders limit and impair the capacity to ingest, digest, absorb or metabolize in a four step process by the body to become the biologically active L-Methylfolate. Unmetabolized level of folic acid were found in 78% of plasma samples from women given 400 mcg of folic acid per day. Unmetabolized folic acid has a high affinity to bind to the cellular folate transport mechanism. This has been shown to reduce the transfer of the active metabolite L-Methylfolate across the blood brain barrier.


Each film coated tablet contains:

  • L-Methylfolate …………… 400mcg


Foli Pill™ tablet are for the specific dietary management of impaired metabolic processes in those women with distinct nutritional requirements for any of the following conditions:

  • Hyperhomocysteinemia during pregnancy.
  • High risk recurrent pregnancy loss,
  • Impaired folic acid absorption and impaired metabolism.


Red blood cell (RBCs) appear to be the storage depot for folate, as RBC levels remain elevated for periods in excess of 40 days following discontinuation of supplementation. Plasma protein binding studies showed that L-Methylfolate is 56% bound to plasma proteins.

Patient Information:

Foli Pill™ are a medical food.

Dosage and Administration:

1 or 2 tablets daily

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Folates when administered as a single agent in doses above 0.1mg daily, may obscure pernicious anemia in that hematologic remission can occur while neurological manifestations remain progressive.

Adverse reaction:

While allergic sensitization has been reported following both oral and parenteral administration of folic acid, allergic sensitization has not been reported with the use of Foli Pill™.


Known hypersensitivity to any of the components in the product is a contraindication.


Store in a cool & dry place below 30oc. Protect from light & moisture.


Foli Pill™ is available in a pack of 30 tablets.